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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKM
All Species:
32.73
Human Site:
S303
Identified Species:
51.43
UniProt:
P06732
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06732
NP_001815.2
381
43101
S303
H
V
K
L
A
H
L
S
K
H
P
K
F
E
E
Chimpanzee
Pan troglodytes
XP_001163660
381
42901
S303
H
V
K
L
A
H
L
S
K
H
P
K
F
E
E
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
G303
H
I
K
L
P
H
L
G
K
H
E
K
F
S
E
Dog
Lupus familis
XP_533641
488
54723
S410
H
V
K
L
A
H
L
S
K
H
P
K
F
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P07310
381
43026
S303
H
V
K
L
A
N
L
S
K
H
P
K
F
E
E
Rat
Rattus norvegicus
P07335
381
42707
G303
H
I
K
L
P
H
L
G
K
H
E
K
F
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
L262
D
I
L
K
K
L
R
L
Q
K
R
G
T
G
G
Chicken
Gallus gallus
P00565
381
43310
S303
H
V
K
L
P
K
L
S
Q
H
P
K
F
E
E
Frog
Xenopus laevis
NP_001080073
381
42887
S303
H
A
K
L
P
N
L
S
K
H
P
K
F
E
E
Zebra Danio
Brachydanio rerio
NP_571007
381
42806
S303
H
V
K
L
P
K
L
S
T
H
A
K
F
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
S292
I
K
V
P
K
L
A
S
N
K
A
K
L
E
E
Honey Bee
Apis mellifera
O61367
355
39990
A291
I
K
L
P
K
L
A
A
N
R
A
K
L
E
E
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
S295
H
I
K
L
P
K
I
S
A
K
D
D
F
K
K
Sea Urchin
Strong. purpuratus
P18294
1174
130851
S717
H
V
K
L
P
L
L
S
K
Y
P
R
F
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
G303
H
I
K
L
P
H
L
G
K
H
E
K
F
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
80.5
75.1
N.A.
96.5
79.5
N.A.
70.3
90.2
88.7
88.7
N.A.
42.5
40.4
37.5
22.4
Protein Similarity:
100
97.3
90.2
77.4
N.A.
98.9
89.5
N.A.
78.2
95.8
95.5
94.2
N.A.
58.7
59
55.3
27.8
P-Site Identity:
100
100
66.6
100
N.A.
93.3
66.6
N.A.
0
80
80
73.3
N.A.
26.6
20
33.3
60
P-Site Similarity:
100
100
73.3
100
N.A.
100
73.3
N.A.
13.3
86.6
86.6
73.3
N.A.
26.6
26.6
60
86.6
Percent
Protein Identity:
N.A.
79.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
89.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
27
0
14
7
7
0
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
7
7
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
20
0
0
60
80
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
0
0
0
7
0
7
7
% G
% His:
80
0
0
0
0
40
0
0
0
67
0
0
0
0
0
% H
% Ile:
14
34
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
14
80
7
20
20
0
0
60
20
0
80
0
7
7
% K
% Leu:
0
0
14
80
0
27
74
7
0
0
0
0
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
14
0
0
14
0
0
0
0
0
0
% N
% Pro:
0
0
0
14
54
0
0
0
0
0
47
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
7
0
0
7
7
7
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% T
% Val:
0
47
7
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _